Adenosine A2A Receptors Modulate Acute Injury and Neuroinflammation in Brain Ischemia
The extracellular concentration of adenosine in the brain increases dramatically during ischemia.Adenosine A2A receptor is expressed in neurons and glial cells and in inflammatory cells (lymphocytes and granulocytes).Recently, adenosine A2A receptor emerged as a potential therapeutic attractive target in ischemia.Ischemia is a multifactorial pathol